Sodium Hyaluronate API

Product Name: Sodium Hyaluronate/Hyaluronic Acid

CAS: 9067-32-7

Assay: 95.0%~105.0%

Intrinsic Viscosity: Measured value m³/kg

Molecular Weight: 800-3million Da

Function: 

Sodium Hyaluronate has been widely used in the industry of nutraceuticals.

It can be digested and absorbed, making the skin moist, smooth, soft and elastic; delaying aging and preventing the occurrence of arthritis and brain atrophy

Sodium hyaluronate is a glycosaminoglycan that is an important structural component of joint cartilage and is responsible for the viscosity (thickness) of the synovial fluid.

We have a wide range of Sodium Hyaluronate fom 800-300W mocelur weight for you to choose to adopt different products.

Shelf life: 2 years

Description

Hyaluronic acid, also known as hyaluronan, HA and uronic acid, is a linear polysaccharide composed of repeating disaccharide units of D-glucuronic acid and N-acetyl-glucosamine

It is not sulfated or covalently bound to proteins, but exists in the form of free or noncovalent complexes. Its structure is simple but the relative molecular weight is very large.

MTOE Grade Specification

Test Items Standard Test Items Standard
Appearance White or almost white powder or granule Iron/(mg/kg) ≤ 80
Identification A.Infrared absorption spectrophotomet Bacteria counts/(CFU/g) ≤100
B.It gives reaction(a)of sodium Molds and yeasts(CFU/g) ≤50
Loss on drying ≤15.0% Staphylococcus aureus/g Negative
Intrinsic viscosity/

(m³/kg)

Measured value Pseudomonas aeruginosa/g Negative
Molecular weight/(Da) Measured value Bacterial endotoxins/(IU/mg) <0.5
pH 5.0-8.5 Hemolysis Negative
Nucleic Acid A260nm≤ 0.5 Hemolytic streptococci Negative
Appearance of Solution A600nm≤ 0.01 Ethanol residues/(ppm) ≤4000
Protein/% ≤0.1 Sodium hyaluronate/(%) 95-105
Chlorides/% ≤ 0.5 / /

 

Application:

  1. Ophthalmic Surgery
  • Protects corneal endothelial cells from surgical instrument damage
  • Maintain the depth and shape of the anterior chamber of eyes for easy      surgical operation
  • Provides a clear surgical field for the surgeon
  • Provides a viscoelastic space that facilitates the placement of the implant

  1. Articular Cartilage
  • Lubrication, reduce friction
  • Prevent cartilage degradation, protect cartilage, and promote cartilage formation
  • Masking membrane sensation, relieving pain
  • Regulates cellular function and inhibits angiogenesis

  1. Wound Healing
  • HA accelerates the migration rate of injured epithelial cells and promotes the mobilization of macrophages necessary for wound healing.
  • HA also transports certain proteins and peptides such as growth factors to the wound parts, which plays an important role in wound healing.

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